Northampton will be looking to maintain their playoff position and are still within striking distance of an automatic promotion place. Big man Adebayo Akinfenwa is a heavy load for any defence to handle and will want to add to his tally of 17 goals this season.
Plymouth have been on a decent run for a side that sit third from bottom on goal difference but manager John Sheridan is urging his players for better performances especially after a dismal home defeat against Oxford after looking like they were building momentum. They have a bad record against top half teams away but January additions Jason Banton and Rueben Reid have improved the forward line.
The Pilgrims will be desperate for points before a six pointer on Tuesday night versus Wimbledon.